So my question to you would be are you allergic to silicone? I am allergic to latex but my coworker is allergic to anything silicone so between the two of us, work can be rather amusing on who can help which customer with what. Just a thought.

Yes, my daughter and I both have latex allergies and we have been experiencing severely itchy palms and fingers, along with blistering and tiny fluid filled bumps that suggest a contact allergy. We have tried for over 2 months to identify the problem, along with visiting the primary care doctor and then sent to the specialist with blood work up.
My daughter unwittingly purchased a new case as she wanted one that would fit into her pocket. We began to notice that her allergy went away while mine continued. We finally put the information together and identified the otter box as the potential problem. Very frustrating with ongoing discomfort and costly medical/lab bills.
Sounds like latex gloves are used in processing & packaging of the otter box; seems like the company should adopt a policy of the use of the latex-free gloves, or put the disclaimer on the box.
I e washed the otter box case with warm soapy water & rinsed well, as the article suggested, yet this has not solved the problem. We may need to take the cases back for a refund, w/return as used but defective. Bummer, as I really like the protection for the phone that this case provided, but this is not tolerable.

Oh my goodness, I am having the same problem with underskin blisters on my fingers. Mine can erupt into full-blown blisters. My dermatologist was puzzled and tested my blood for so many things and came back with nothing.
Just put it together today that it could be my Otterbox. I’m taking it off immediately and seeing if it helps.

Hey there Elizabeth, I’m having the same problem it seems! Did you have any luck?